Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.D1145Y

c.3433G>T

Surrounding Variants

2 papers

NM_005120.3

p.E1144G

c.3431A>G

4 papers

NM_005120.3

p.E1144Q

c.3430G>C

32 papers

NM_005120.3

p.R1148H

c.3443G>A

1 paper

NM_005120.3

p.A1150T

c.3448G>A

1 paper

NM_005120.3

p.A1150S

c.3448G>T

1 paper

NM_005120.3

p.A1150D

c.3449C>A

1 paper

NM_005120.3

p.I1152V

c.3454A>G

1 paper

NM_005120.3

p.R1138G

c.3412C>G

7 papers

NM_005120.3

p.R1138W

c.3412C>T

1 paper

NM_005120.3

p.P1153T

c.3457C>A

1 paper

NM_005120.3

p.A1137T

c.3409G>A

1 paper

NM_005120.3

p.L1155R

c.3464T>G