Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.A1219P

c.3655G>C

Surrounding Variants

3 papers

NM_005120.3

p.G1218E

c.3653G>A

1 paper

NM_005120.3

p.G1218V

c.3653G>T

2 papers

NM_005120.3

p.V1220M

c.3658G>A

1 paper

NM_005120.3

p.G1218R

c.3652G>A

1 paper

NM_005120.3

p.G1218R

c.3652G>C

2 papers

NM_005120.3

p.V1220E

c.3659T>A

1 paper

NM_005120.3

p.F1221L

c.3661T>C

1 paper

NM_005120.3

p.F1221L

c.3663T>A

1 paper

NM_005120.3

p.F1221L

c.3663T>G

5 papers

NM_005120.3

p.V1216M

c.3646G>A

1 paper

NM_005120.3

p.A1222S

c.3664G>T

1 paper

NM_005120.3

p.A1222G

c.3665C>G