Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

1–12 of 96 variants

5 papers

NM_001003891.3

p.Q179_Q180ins1

c.537_538insCAG

5 papers

NM_001003891.3

p.Q262del1

c.784_785delCAG

4 papers

NM_001003891.3

p.Q262_A263ins1

c.786_787insCAG

3 papers

NM_001003891.3

p.Q250_Q251insFs

c.750_751ins4

3 papers

NM_001003891.3

p.K537_Q538insCAG

c.1609_1613ins9

3 papers

NM_001003891.3

p.Q750_S751ins4

c.2248_2252ins12

2 papers

NM_001003891.3

p.Q174del1

c.520_521delCAG

2 papers

NM_001003891.3

p.Q184del1

c.550_551delCAG

2 papers

NM_001003891.3

p.Q253_Q254ins2

c.759_760ins6

2 papers

NM_001003891.3

p.M378L

c.1132A>C

2 papers

NM_001003891.3

p.M378L

c.1132A>T

2 papers

NM_001003891.3

p.Q750_S751insCAG

c.2248_2252ins9