Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001003891.3

p.Q174del1

c.520_521delCAG

Surrounding Variants

1 paper

NM_001003891.3

p.A175G

c.524C>G

5 papers

NM_001003891.3

p.Q179_Q180ins1

c.537_538insCAG

2 papers

NM_001003891.3

p.Q184del1

c.550_551delCAG

1 paper

NM_001003891.3

p.Q178*

c.532C>T

1 paper

NM_001003891.3

p.Q179_Q180insFs

c.537_538ins4

1 paper

NM_001003891.3

p.Q179fs

c.535_536fs

1 paper

NM_001003891.3

p.Q179insFs

c.536_537insGC

1 paper

NM_001003891.3

p.Q182Q

c.546G>A

1 paper

NM_001003891.3

p.Q185del1

c.553_554delCAA

1 paper

NM_001003891.3

p.Q188L

c.563A>T

1 paper

NM_001003891.3

p.F200fs

c.598_599fs

1 paper

NM_001003891.3

p.Q209del1

c.625_626delCAG