Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001003891.3

p.Q261_Q262del0

c.781_786del6

Surrounding Variants

4 papers

NM_001003891.3

p.Q262_A263ins1

c.786_787insCAG

2 papers

NM_001003891.3

p.Q253_Q254ins2

c.759_760ins6

3 papers

NM_001003891.3

p.Q250_Q251insFs

c.750_751ins4

5 papers

NM_001003891.3

p.Q262del1

c.784_785delCAG

1 paper

NM_001003891.3

p.Q250Fs

c.750delinsACAFs

1 paper

NM_001003891.3

p.Q250insFs

c.749_750insGC

1 paper

NM_001003891.3

p.Q250fs

c.748_749fs

1 paper

NM_001003891.3

p.L244M

c.730C>A

1 paper

NM_001003891.3

p.A242A

c.726A>T

1 paper

NM_001003891.3

p.A263V

c.788C>T

1 paper

NM_001003891.3

p.Q237_L238insT

c.709_713ins3

1 paper

NM_001003891.3

p.P274L

c.821C>T