Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001003891.3

p.M378L

c.1132A>T

Surrounding Variants

2 papers

NM_001003891.3

p.M378L

c.1132A>C

1 paper

NM_001003891.3

p.M378I

c.1134G>A

1 paper

NM_001003891.3

p.M378I

c.1134G>C

1 paper

NM_001003891.3

p.M378I

c.1134G>T

1 paper

NM_001003891.3

p.Q384_M385Splc

c.1152+7G>A

1 paper

NM_001003891.3

p.F347_V348Splc

c.1041+1G>A

1 paper

NM_001003891.3

p.L345L

c.1035G>C

1 paper

NM_001003891.3

p.L334V

c.1000C>G

1 paper

NM_001003891.3

p.Q321R

c.962A>G

1 paper

NM_001003891.3

p.Q289ins1

c.866_867insCAG

1 paper

NM_001003891.3

p.P274L

c.821C>T

1 paper

NM_001003891.3

p.A263V

c.788C>T