Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001003891.3

p.M566T

c.1697T>C

Surrounding Variants

1 paper

NM_001003891.3

p.D575delFs

c.1723_1724delGA

1 paper

NM_001003891.3

p.S540_K541insCAG

c.1618_1622ins9

3 papers

NM_001003891.3

p.K537_Q538insCAG

c.1609_1613ins9

1 paper

NM_001003891.3

p.K537_Q538ins4

c.1609_1613ins12

1 paper

NM_001003891.3

p.L536_K537insGC

c.1606_1610ins6

1 paper

NM_001003891.3

p.Y532_D534del3

c.1594_1601del9

1 paper

NM_001003891.3

p.Q531_Y532insCAG

c.1591_1595ins9

1 paper

NM_001003891.3

p.G523C

c.1567G>T

1 paper

NM_001003891.3

p.S520_A522del3

c.1558_1565del9

1 paper

NM_001003891.3

p.V513Splc

c.1538-1G>A

1 paper

NM_001003891.3

p.L509S

c.1526T>C

1 paper

NM_001003891.3

p.P508S

c.1522C>T