Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001003891.3

p.T661_R662delFs

c.1982_1985del4

Surrounding Variants

1 paper

NM_001003891.3

p.R664C

c.1990C>T

1 paper

NM_001003891.3

p.E670_R671delFs

c.2009_2012del4

1 paper

NM_001003891.3

p.P687_K688delFs

c.2060_2063del4

1 paper

NM_001003891.3

p.D694N

c.2080G>A

1 paper

NM_001003891.3

p.R630H

c.1889G>A

1 paper

NM_001003891.3

p.S631_V633del3

c.1891_1898del9

1 paper

NM_001003891.3

p.R630_S631insCAG

c.1888_1892ins9

1 paper

NM_001003891.3

p.Q619Q

c.1857G>A

1 paper

NM_001003891.3

p.Y616_L617delFs

c.1847_1850del4

1 paper

NM_001003891.3

p.T603A

c.1807A>G

1 paper

NM_001003891.3

p.A727_D728delFs

c.2180_2183del4

1 paper

NM_001003891.3

p.D728fs

c.2182_2183fs