Varaico: Literature-Extracted Genetic Variants

MED15

90 papers

RefSeq Summary

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains st...

Pfam Domains

Med15_Naa 1–51UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Naa 6–77UCSCARC105/Med15 mediator subunit N-terminal KIX domain

Med15_Maa 462–581UCSCARC105/Med15 mediator subunit central domain

Med15_Caa 608–716UCSCARC105/Med15 mediator subunit C-terminal domain

Gene Aliases

HGNC Name

mediator complex subunit 15

HGNC Previous Symbols

TNRC7; PCQAP

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001003891.3

p.Q750_S751insCAG

c.2248_2252ins9

Surrounding Variants

3 papers

NM_001003891.3

p.Q750_S751ins4

c.2248_2252ins12

1 paper

NM_001003891.3

p.S751_H753del3

c.2251_2258del9

1 paper

NM_001003891.3

p.L749_Q750insGC

c.2245_2249ins6

1 paper

NM_001003891.3

p.S751L

c.2252C>T

1 paper

NM_001003891.3

p.H753_R754insCAG

c.2257_2261ins9

1 paper

NM_001003891.3

p.P747S

c.2239C>T

1 paper

NM_001003891.3

p.R759_L760ins6

c.2275_2279ins18

2 papers

NM_001003891.3

p.C784_S786del3

c.2350_2357del9

1 paper

NM_001003891.3

p.S786_A787insCAG

c.2356_2360ins9

1 paper

NM_001003891.3

p.D728fs

c.2182_2183fs

1 paper

NM_001003891.3

p.A727_D728delFs

c.2180_2183del4

1 paper

NM_001003891.3

p.D694N

c.2080G>A