Varaico: Literature-Extracted Genetic Variants

MED25

144 papers

RefSeq Summary

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded ...

Pfam Domains

Med25_VWAaa 12–226UCSCMediator complex subunit 25 von Willebrand factor type A

Med25_SD1aa 234–383UCSCMediator complex subunit 25 synapsin 1

Med25aa 396–546UCSCMediator complex subunit 25 PTOV activation and synapsin 2

zf-C2H2_12aa 729–791UCSCSpin-doc/GT2D2, zinc finger domain

Gene Aliases

HGNC Name

mediator complex subunit 25

HGNC Alias Symbols

ARC92; ACID1; TCBAP0758; DKFZp434K0512

Papers

RefSeq ID

Protein change

DNA change

1–12 of 120 variants

26 papers

NM_030973.4

p.A335V

c.1004C>T

13 papers

NM_030973.4

p.Y39C

c.116A>G

10 papers

NM_030973.4

p.R140W

c.418C>T

7 papers

NM_030973.4

p.I173T

c.518T>C

5 papers

NM_030973.4

p.R132C

c.394C>T

4 papers

NM_030973.4

p.G106R

c.316G>A

3 papers

NM_030973.4

p.P78A

c.232C>G

3 papers

NM_030973.4

p.G106R

c.316G>C

3 papers

NM_030973.4

p.D126V

c.377A>T

3 papers

NM_030973.4

p.Q451E

c.1351C>G

3 papers

NM_030973.4

p.Q593delFs

c.1778_1779delAG

3 papers

NM_030973.4

p.Q593fs

c.1777_1778fs