Varaico: Literature-Extracted Genetic Variants

MED25

144 papers

RefSeq Summary

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded ...

Pfam Domains

Med25_VWAaa 12–226UCSCMediator complex subunit 25 von Willebrand factor type A

Med25_SD1aa 234–383UCSCMediator complex subunit 25 synapsin 1

Med25aa 396–546UCSCMediator complex subunit 25 PTOV activation and synapsin 2

zf-C2H2_12aa 729–791UCSCSpin-doc/GT2D2, zinc finger domain

Gene Aliases

HGNC Name

mediator complex subunit 25

HGNC Alias Symbols

ARC92; ACID1; TCBAP0758; DKFZp434K0512

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_030973.4

p.D126V

c.377A>T

Surrounding Variants

1 paper

NM_030973.4

p.Q123R

c.368A>G

1 paper

NM_030973.4

p.R132fs

c.394_395fs

5 papers

NM_030973.4

p.R132C

c.394C>T

1 paper

NM_030973.4

p.R132delFs

c.396delC

1 paper

NM_030973.4

p.T120fs

c.358_359fs

1 paper

NM_030973.4

p.T120_A121delFs

c.359_362del4

4 papers

NM_030973.4

p.G106R

c.316G>A

3 papers

NM_030973.4

p.G106R

c.316G>C

1 paper

NM_030973.4

p.M104L

c.310A>T

1 paper

NM_030973.4

p.T138M

c.413C>T

10 papers

NM_030973.4

p.R140W

c.418C>T

1 paper

NM_030973.4

p.P150Q

c.449C>A