Varaico: Literature-Extracted Genetic Variants

MED25

144 papers

RefSeq Summary

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded ...

Pfam Domains

Med25_VWAaa 12–226UCSCMediator complex subunit 25 von Willebrand factor type A

Med25_SD1aa 234–383UCSCMediator complex subunit 25 synapsin 1

Med25aa 396–546UCSCMediator complex subunit 25 PTOV activation and synapsin 2

zf-C2H2_12aa 729–791UCSCSpin-doc/GT2D2, zinc finger domain

Gene Aliases

HGNC Name

mediator complex subunit 25

HGNC Alias Symbols

ARC92; ACID1; TCBAP0758; DKFZp434K0512

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030973.4

p.P206L

c.617C>T

Surrounding Variants

1 paper

NM_030973.4

p.A202fs

c.604_605fs

1 paper

NM_030973.4

p.P201fs

c.601_602fs

1 paper

NM_030973.4

p.P201A

c.601C>G

1 paper

NM_030973.4

p.P201fs

c.601_602fs

1 paper

NM_030973.4

p.A199fs

c.595_596fs

1 paper

NM_030973.4

p.P201delFs

c.602delC

1 paper

NM_030973.4

p.E196K

c.586G>A

1 paper

NM_030973.4

p.L193R

c.578T>G

1 paper

NM_030973.4

p.R224G

c.670C>G

1 paper

NM_030973.4

p.V227M

c.679G>A

1 paper

NM_030973.4

p.V230A

c.689T>C

1 paper

NM_030973.4

p.F180L

c.540C>G