Varaico: Literature-Extracted Genetic Variants

MED25

144 papers

RefSeq Summary

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded ...

Pfam Domains

Med25_VWAaa 12–226UCSCMediator complex subunit 25 von Willebrand factor type A

Med25_SD1aa 234–383UCSCMediator complex subunit 25 synapsin 1

Med25aa 396–546UCSCMediator complex subunit 25 PTOV activation and synapsin 2

zf-C2H2_12aa 729–791UCSCSpin-doc/GT2D2, zinc finger domain

Gene Aliases

HGNC Name

mediator complex subunit 25

HGNC Alias Symbols

ARC92; ACID1; TCBAP0758; DKFZp434K0512

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030973.4

p.M367_A368Splc

c.1101+4G>A

Surrounding Variants

1 paper

NM_030973.4

p.P362R

c.1085C>G

1 paper

NM_030973.4

p.T359_P362del4

c.1075_1085del12

1 paper

NM_030973.4

p.S348S

c.1044C>T

26 papers

NM_030973.4

p.A335V

c.1004C>T

1 paper

NM_030973.4

p.L328insFs

c.983_984insC

1 paper

NM_030973.4

p.P326S

c.976C>T

1 paper

NM_030973.4

p.G317C

c.949G>T

1 paper

NM_030973.4

p.R302H

c.905G>A

1 paper

NM_030973.4

p.P301S

c.901C>T

2 papers

NM_030973.4

p.G300D

c.899G>A

1 paper

NM_030973.4

p.G300S

c.898G>A

2 papers

NM_030973.4

p.Q286*

c.856C>T