Varaico: Literature-Extracted Genetic Variants

MED25

144 papers

RefSeq Summary

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded ...

Pfam Domains

Med25_VWAaa 12–226UCSCMediator complex subunit 25 von Willebrand factor type A

Med25_SD1aa 234–383UCSCMediator complex subunit 25 synapsin 1

Med25aa 396–546UCSCMediator complex subunit 25 PTOV activation and synapsin 2

zf-C2H2_12aa 729–791UCSCSpin-doc/GT2D2, zinc finger domain

Gene Aliases

HGNC Name

mediator complex subunit 25

HGNC Alias Symbols

ARC92; ACID1; TCBAP0758; DKFZp434K0512

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030973.4

p.F494L

c.1482C>G

Surrounding Variants

1 paper

NM_030973.4

p.F494L

c.1482C>A

1 paper

NM_030973.4

p.F494L

c.1480T>C

1 paper

NM_030973.4

p.S482F

c.1445C>T

1 paper

NM_030973.4

p.E481_S482insFs

c.1443_1444insG

1 paper

NM_030973.4

p.L480V

c.1438C>G

1 paper

NM_030973.4

p.N477S

c.1430A>G

1 paper

NM_030973.4

p.L458_T459Splc

c.1375-55T>C

3 papers

NM_030973.4

p.Q451E

c.1351C>G

1 paper

NM_030973.4

p.L448L

c.1344G>A

1 paper

NM_030973.4

p.K447E

c.1339A>G

1 paper

NM_030973.4

p.W444R

c.1330T>A

1 paper

NM_030973.4

p.W444R

c.1330T>C