Varaico: Literature-Extracted Genetic Variants

Gene:MEN1
Variant:p.S459_R460insFs

MEN1

1,357 papers

RefSeq Summary

This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic g...

Pfam Domains

Meninaa 1–146UCSCMenin
Meninaa 1–510UCSCMenin
Meninaa 364–552UCSCMenin
Meninaa 515–608UCSCMenin

Gene Aliases

HGNC Name

menin 1

HGNC Previous Name

multiple endocrine neoplasia I

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_001370259.2
p.S459_R460insFs
c.1377_1378insG
Surrounding Variants
1 paper
NM_001370259.2
p.V458_S459delFs
c.1373_1376del4
72 papers
NM_001370259.2
p.R460*
c.1378C>T
1 paper
NM_001370259.2
p.V458Fs
c.1372delinsGTCGGGFs
1 paper
NM_001370259.2
p.V458A
c.1373T>C
2 papers
NM_001370259.2
p.E461insFs
c.1381_1382insG
1 paper
NM_000244.4
p.E466fs
c.1396_1397fs
1 paper
NM_001370259.2
p.E461delFs
c.1382delT
1 paper
NM_001370259.2
p.I457_E461del0
c.1371_1382del12
1 paper
NM_001370259.2
p.I457T
c.1370T>C
2 papers
NM_001370259.2
p.A462P
c.1384G>C
1 paper
NM_001370259.2
p.E461delFs
c.1382_1383delCT
2 papers
NM_001370259.2
p.R452_R456del0
c.1356_1367del12
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