Varaico: Literature-Extracted Genetic Variants

Gene:MEN1
Variant:p.L409delFs

MEN1

1,357 papers

RefSeq Summary

This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic g...

Pfam Domains

Meninaa 1–146UCSCMenin
Meninaa 1–510UCSCMenin
Meninaa 364–552UCSCMenin
Meninaa 515–608UCSCMenin

Gene Aliases

HGNC Name

menin 1

HGNC Previous Name

multiple endocrine neoplasia I

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000244.4
p.L409delFs
c.1227delG
Surrounding Variants
1 paper
NM_001370259.2
p.Q405_D406insFs
c.1215_1216insAA
14 papers
NM_001370259.2
p.Q405*
c.1213C>T
1 paper
NM_001370259.2
p.D406insFs
c.1216_1217insA
1 paper
NM_001370259.2
p.S399_Q405del7
c.1195_1214del21
1 paper
NM_001370259.2
p.L404fs
c.1210_1211fs
2 papers
NM_001370259.2
p.A403delFs
c.1209delG
2 papers
NM_001370259.2
p.A403T
c.1207G>A
1 paper
NM_001370259.2
p.E408Q
c.1222G>C
2 papers
NM_001370259.2
p.E408K
c.1222G>A
2 papers
NM_001370259.2
p.C409fs
c.1225_1226fs
2 papers
NM_001370259.2
p.E408_C409insFs
c.1224_1225ins4
1 paper
NM_001370259.2
p.G401D
c.1202G>A
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