Varaico: Literature-Extracted Genetic Variants

MERTK

1,393 papers

RefSeq Summary

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one ...

Pfam Domains

igaa 104–185UCSCImmunoglobulin domain

Ig_3aa 197–266UCSCImmunoglobulin domain

fn3aa 285–376UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 587–854UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MER proto-oncogene, tyrosine kinase

HGNC Alias Symbols

mer; RP38; c-Eyk; Tyro12

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006343.3

p.I902fs

c.2704_2705fs

Surrounding Variants

1 paper

NM_006343.3

p.I902_A904delFs

c.2704_2711del8

1 paper

NM_006343.3

p.P899S

c.2695C>T

1 paper

NM_006343.3

p.C906_T907del2

c.2716_2720del6

1 paper

NM_006343.3

p.I897V

c.2689A>G

1 paper

NM_006343.3

p.T907I

c.2720C>T

1 paper

NM_006343.3

p.R909C

c.2725C>T

3 papers

NM_006343.3

p.R909H

c.2726G>A

1 paper

NM_006343.3

p.P892Q

c.2675C>A

1 paper

NM_006343.3

p.A885V

c.2654C>T

1 paper

NM_006343.3

p.A885T

c.2653G>A

1 paper

NM_006343.3

p.V919F

c.2755G>T

1 paper

NM_006343.3

p.E926Q

c.2776G>C