Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000245.4

p.M1I

c.3G>A

Surrounding Variants

2 papers

NM_000245.4

p.M1delins

c.3delinsAAAC

1 paper

NM_000245.4

p.M1I

c.3G>C

2 papers

NM_000245.4

p.M1Fs

c.3delinsCCFs

1 paper

NM_000245.4

p.M1Fs

c.3delinsCTTFs

1 paper

NM_000245.4

p.M1_K2insFs

c.3_4insA

1 paper

NM_000245.4

p.K2Fs

c.4delinsACACAFs

2 papers

NM_000245.4

p.M1Fs

c.3delinsGTFs

2 papers

NM_000245.4

p.M1I

c.3G>T

4 papers

NM_000245.4

p.M1Fs

c.3delinsTTFs

1 paper

NM_000245.4

p.M1Fs

c.3delinsTTTFs

1 paper

NM_000245.4

p.K2delins

c.4delinsA

2 papers

NM_000245.4

p.K2Fs

c.4delinsACCFs