Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.A3Fs

c.7delinsTTAAAACTGFs

Surrounding Variants

1 paper

NM_000245.4

p.K2delins

c.6delinsA

3 papers

NM_000245.4

p.K2N

c.6G>C

2 papers

NM_000245.4

p.K2N

c.6G>T

1 paper

NM_000245.4

p.A3delins

c.7delinsG

3 papers

NM_000245.4

p.A3Fs

c.7delinsGGFs

2 papers

NM_000245.4

p.K2delins

c.5delinsG

3 papers

NM_000245.4

p.K2M

c.5A>T

1 paper

NM_000245.4

p.A3insFs

c.9dupC

2 papers

NM_000245.4

p.A3delFs

c.9delC

2 papers

NM_000245.4

p.K2Fs

c.4delinsACCFs

1 paper

NM_000245.4

p.K2insFs

c.4_5insT

2 papers

NM_000245.4

p.K2delins

c.4delinsC