Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.V6L

c.16G>T

Surrounding Variants

1 paper

NM_000245.4

p.V6L

c.16G>C

2 papers

NM_000245.4

p.A5delins

c.15delinsA

1 paper

NM_000245.4

p.V6E

c.17T>A

1 paper

NM_000245.4

p.V6delins

c.17delinsAGAA

1 paper

NM_000245.4

p.V6Fs

c.16delinsGTATTTCAGTTTAGFs

2 papers

NM_000245.4

p.A5delins

c.14delinsA

1 paper

NM_000245.4

p.A5G

c.14C>G

1 paper

NM_000245.4

p.A5V

c.14C>T

1 paper

NM_000245.4

p.V6V

c.18G>T

1 paper

NM_000245.4

p.L7Fs

c.19delinsATTGGFs

7 papers

NM_000245.4

p.A5T

c.13G>A

2 papers

NM_000245.4

p.A5Fs

c.13delinsAAAFs