Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.G10delins

c.29delinsG

Surrounding Variants

1 paper

NM_000245.4

p.G10Fs

c.29delinsACCTAFs

2 papers

NM_000245.4

p.G10Fs

c.28delinsGGFs

4 papers

NM_000245.4

p.P9Fs

c.26delinsAGACGFs

1 paper

NM_000245.4

p.P9ins1

c.26_27insGGT

2 papers

NM_000245.4

p.P9delins

c.26delinsG

2 papers

NM_000245.4

p.P9Fs

c.26delinsGGTFs

2 papers

NM_000245.4

p.P9T

c.25C>A

1 paper

NM_000245.4

p.P9Fs

c.25delinsCGAFs

1 paper

NM_000245.4

p.P9S

c.25C>T

1 paper

NM_000245.4

p.P9delFs

c.25delC

1 paper

NM_000245.4

p.I11T

c.32T>C

1 paper

NM_000245.4

p.A8E

c.23C>A