Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.L12fs

c.34_35fs

Surrounding Variants

1 paper

NM_000245.4

p.L12F

c.34C>T

1 paper

NM_000245.4

p.I11M

c.33C>G

2 papers

NM_000245.4

p.L12P

c.35T>C

1 paper

NM_000245.4

p.L12L

c.36C>T

1 paper

NM_000245.4

p.I11T

c.32T>C

1 paper

NM_000245.4

p.V13M

c.37G>A

5 papers

NM_000245.4

p.V13L

c.37G>C

3 papers

NM_000245.4

p.V13L

c.37G>T

1 paper

NM_000245.4

p.L14_L18del0

c.40_54del15

1 paper

NM_000245.4

p.V13E

c.38T>A

1 paper

NM_000245.4

p.V13V

c.39G>A

1 paper

NM_000245.4

p.G10Fs

c.29delinsACCTAFs