Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000245.4

p.L14H

c.41T>A

Surrounding Variants

1 paper

NM_000245.4

p.L14P

c.41T>C

1 paper

NM_000245.4

p.L14R

c.41T>G

3 papers

NM_000245.4

p.L14I

c.40C>A

1 paper

NM_000245.4

p.L14V

c.40C>G

7 papers

NM_000245.4

p.L14F

c.40C>T

1 paper

NM_000245.4

p.L14L

c.42C>T

1 paper

NM_000245.4

p.V13V

c.39G>A

1 paper

NM_000245.4

p.L14_F16del3

c.40_47del9

1 paper

NM_000245.4

p.V13E

c.38T>A

1 paper

NM_000245.4

p.L15Q

c.44T>A

1 paper

NM_000245.4

p.V13M

c.37G>A

5 papers

NM_000245.4

p.V13L

c.37G>C