Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.F16L

c.48T>A

Surrounding Variants

2 papers

NM_000245.4

p.T17N

c.50C>A

1 paper

NM_000245.4

p.L18insFs

c.52_53insCT

2 papers

NM_000245.4

p.T17I

c.50C>T

1 paper

NM_000245.4

p.F16I

c.46T>A

1 paper

NM_000245.4

p.F16V

c.46T>G

1 paper

NM_000245.4

p.T17_L18insFs

c.51_52insCT

2 papers

NM_000245.4

p.L18insFs

c.53dupT

1 paper

NM_000245.4

p.L15Q

c.44T>A

1 paper

NM_000245.4

p.L14L

c.42C>T

1 paper

NM_000245.4

p.L18F

c.54G>C

1 paper

NM_000245.4

p.L18_V19insFs

c.54_55insCT

1 paper

NM_000245.4

p.L18_V19insFs

c.54_55insT