Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.G24E

c.71G>A

Surrounding Variants

1 paper

NM_000245.4

p.E25E

c.75G>A

1 paper

NM_000245.4

p.E25D

c.75G>C

1 paper

NM_000245.4

p.E25D

c.75G>T

1 paper

NM_000245.4

p.S22R

c.66C>A

1 paper

NM_000245.4

p.S22R

c.66C>G

1 paper

NM_000245.4

p.N23del1

c.67_68delAAT

1 paper

NM_000245.4

p.C26S

c.76T>A

1 paper

NM_000245.4

p.C26_K27insGGT

c.76_80ins9

1 paper

NM_000245.4

p.S22N

c.65G>A

1 paper

NM_000245.4

p.S22insFs

c.65_66ins22

4 papers

NM_000245.4

p.S22I

c.65G>T

1 paper

NM_000245.4

p.S22R

c.64A>C