Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.K32*

c.94A>T

Surrounding Variants

1 paper

NM_000245.4

p.K32R

c.95A>G

1 paper

NM_000245.4

p.K32K

c.96G>A

1 paper

NM_000245.4

p.A31T

c.91G>A

1 paper

NM_000245.4

p.S33A

c.97T>G

1 paper

NM_000245.4

p.S33Y

c.98C>A

3 papers

NM_000245.4

p.S33C

c.98C>G

2 papers

NM_000245.4

p.S33F

c.98C>T

1 paper

NM_000245.4

p.L30Q

c.89T>A

8 papers

NM_000245.4

p.E34K

c.100G>A

1 paper

NM_000245.4

p.E34Q

c.100G>C

1 paper

NM_000245.4

p.L30delFs

c.88delC

1 paper

NM_000245.4

p.A29V

c.86C>T