Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.M35I

c.105G>T

Surrounding Variants

1 paper

NM_000245.4

p.M35I

c.105G>A

2 papers

NM_000245.4

p.M35I

c.105G>C

1 paper

NM_000245.4

p.M35L

c.103A>C

1 paper

NM_000245.4

p.M35V

c.103A>G

1 paper

NM_000245.4

p.M35L

c.103A>T

1 paper

NM_000245.4

p.N36K

c.108T>A

1 paper

NM_000245.4

p.V37M

c.109G>A

1 paper

NM_000245.4

p.V37L

c.109G>C

1 paper

NM_000245.4

p.V37L

c.109G>T

8 papers

NM_000245.4

p.E34K

c.100G>A

1 paper

NM_000245.4

p.E34Q

c.100G>C

8 papers

NM_000245.4

p.V37A

c.110T>C