Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_000245.4

p.Q42*

c.124C>T

Surrounding Variants

1 paper

NM_000245.4

p.Q42L

c.125A>T

1 paper

NM_000245.4

p.Q42Fs

c.125delinsTTFs

1 paper

NM_000245.4

p.Q42Q

c.126G>A

1 paper

NM_000245.4

p.P44T

c.130C>A

1 paper

NM_000245.4

p.P44S

c.130C>T

1 paper

NM_000245.4

p.P44L

c.131C>T

3 papers

NM_000245.4

p.M39I

c.117G>A

3 papers

NM_000245.4

p.M39I

c.117G>C

3 papers

NM_000245.4

p.M39I

c.117G>T

1 paper

NM_000245.4

p.P44P

c.132C>A

1 paper

NM_000245.4

p.M39K

c.116T>A

1 paper

NM_000245.4

p.M39T

c.116T>C