Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.T50S

c.148A>T

Surrounding Variants

1 paper

NM_000245.4

p.E49_T50insFs

c.147_148ins44

1 paper

NM_000245.4

p.E49D

c.147A>C

1 paper

NM_000245.4

p.E49D

c.147A>T

1 paper

NM_000245.4

p.T50I

c.149C>T

1 paper

NM_000245.4

p.T50delFs

c.150delA

1 paper

NM_000245.4

p.E49G

c.146A>G

11 papers

NM_000245.4

p.E49V

c.146A>T

1 paper

NM_000245.4

p.P51T

c.151C>A

1 paper

NM_000245.4

p.E49K

c.145G>A

1 paper

NM_000245.4

p.E49ins12

c.145_146ins36

2 papers

NM_000245.4

p.P51L

c.152C>T

7 papers

NM_000245.4

p.A48A

c.144G>A