Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.Q53H

c.159G>C

Surrounding Variants

1 paper

NM_000245.4

p.Q53Q

c.159G>A

1 paper

NM_000245.4

p.Q53H

c.159G>T

1 paper

NM_000245.4

p.N54D

c.160A>G

1 paper

NM_000245.4

p.N54I

c.161A>T

2 papers

NM_000245.4

p.Q53*

c.157C>T

1 paper

NM_000245.4

p.V55I

c.163G>A

1 paper

NM_000245.4

p.I52N

c.155T>A

2 papers

NM_000245.4

p.I52F

c.154A>T

1 paper

NM_000245.4

p.V55D

c.164T>A

2 papers

NM_000245.4

p.P51P

c.153C>A

1 paper

NM_000245.4

p.I56V

c.166A>G

1 paper

NM_000245.4

p.I56F

c.166A>T