Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.H61N

c.181C>A

Surrounding Variants

2 papers

NM_000245.4

p.H61Y

c.181C>T

4 papers

NM_000245.4

p.H61R

c.182A>G

4 papers

NM_000245.4

p.H61L

c.182A>T

1 paper

NM_000245.4

p.H60Q

c.180T>A

1 paper

NM_000245.4

p.H60Q

c.180T>G

8 papers

NM_000245.4

p.H60L

c.179A>T

1 paper

NM_000245.4

p.I62V

c.184A>G

1 paper

NM_000245.4

p.H60Y

c.178C>T

1 paper

NM_000245.4

p.E59K

c.175G>A

1 paper

NM_000245.4

p.F63L

c.187T>C

2 papers

NM_000245.4

p.F63V

c.187T>G

1 paper

NM_000245.4

p.H58R

c.173A>G