Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.F63L

c.189C>G

Surrounding Variants

1 paper

NM_000245.4

p.F63L

c.189C>A

1 paper

NM_000245.4

p.L64I

c.190C>A

1 paper

NM_000245.4

p.F63L

c.187T>C

1 paper

NM_000245.4

p.L64P

c.191T>C

2 papers

NM_000245.4

p.F63V

c.187T>G

1 paper

NM_000245.4

p.G65_T67insFs

c.193_200dup8

1 paper

NM_000245.4

p.G65R

c.193G>C

1 paper

NM_000245.4

p.G65C

c.193G>T

1 paper

NM_000245.4

p.I62V

c.184A>G

4 papers

NM_000245.4

p.H61R

c.182A>G

4 papers

NM_000245.4

p.H61L

c.182A>T

1 paper

NM_000245.4

p.A66S

c.196G>T