Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.D94N

c.280G>A

Surrounding Variants

1 paper

NM_000245.4

p.P93Q

c.278C>A

1 paper

NM_000245.4

p.D94E

c.282T>A

3 papers

NM_000245.4

p.P93T

c.277C>A

2 papers

NM_000245.4

p.C95F

c.284G>T

2 papers

NM_000245.4

p.E91G

c.272A>G

1 paper

NM_000245.4

p.P97A

c.289C>G

1 paper

NM_000245.4

p.P97S

c.289C>T

4 papers

NM_000245.4

p.E91K

c.271G>A

2 papers

NM_000245.4

p.P97Q

c.290C>A

2 papers

NM_000245.4

p.P97L

c.290C>T

1 paper

NM_000245.4

p.L90V

c.268C>G

1 paper

NM_000245.4

p.L90L

c.268C>T