Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000245.4

p.C98F

c.293G>T

Surrounding Variants

1 paper

NM_000245.4

p.C98Y

c.293G>A

1 paper

NM_000245.4

p.Q99L

c.296A>T

2 papers

NM_000245.4

p.P97Q

c.290C>A

2 papers

NM_000245.4

p.P97L

c.290C>T

1 paper

NM_000245.4

p.P97A

c.289C>G

1 paper

NM_000245.4

p.P97S

c.289C>T

1 paper

NM_000245.4

p.D100N

c.298G>A

1 paper

NM_000245.4

p.D100_A105delFs

c.300_315del16

5 papers

NM_000245.4

p.C101S

c.301T>A

1 paper

NM_000245.4

p.C101R

c.301T>C

1 paper

NM_000245.4

p.C101G

c.301T>G

2 papers

NM_000245.4

p.C95F

c.284G>T