Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.N106D

c.316A>G

Surrounding Variants

2 papers

NM_000245.4

p.N106T

c.317A>C

1 paper

NM_000245.4

p.L107delFs

c.320delT

1 paper

NM_000245.4

p.A105D

c.314C>A

1 paper

NM_000245.4

p.A105V

c.314C>T

1 paper

NM_000245.4

p.L107fs

c.319_320fs

1 paper

NM_000245.4

p.S108fs

c.322_323fs

1 paper

NM_000245.4

p.S108L

c.323C>T

2 papers

NM_000245.4

p.S103N

c.308G>A

1 paper

NM_000245.4

p.S102R

c.306C>G

1 paper

NM_000245.4

p.G109E

c.326G>A

1 paper

NM_000245.4

p.G109V

c.326G>T

1 paper

NM_000245.4

p.G109G

c.327A>T