Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.S132R

c.394A>C

Surrounding Variants

1 paper

NM_000245.4

p.S132fs

c.394_395fs

1 paper

NM_000245.4

p.S132G

c.394A>G

1 paper

NM_000245.4

p.S132C

c.394A>T

1 paper

NM_000245.4

p.I131I

c.393T>A

1 paper

NM_000245.4

p.S132R

c.396C>A

1 paper

NM_000245.4

p.S132R

c.396C>G

1 paper

NM_000245.4

p.L130H

c.389T>A

1 paper

NM_000245.4

p.C133*

c.399T>A

1 paper

NM_000245.4

p.L130fs

c.388_389fs

2 papers

NM_000245.4

p.L130F

c.388C>T

1 paper

NM_000245.4

p.G134S

c.400G>A

1 paper

NM_000245.4

p.S135C

c.403A>T