Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.S135R

c.405C>G

Surrounding Variants

1 paper

NM_000245.4

p.S135S

c.405C>T

15 papers

NM_000245.4

p.V136I

c.406G>A

3 papers

NM_000245.4

p.S135N

c.404G>A

1 paper

NM_000245.4

p.S135T

c.404G>C

1 paper

NM_000245.4

p.V136_N137del2

c.406_410del6

1 paper

NM_000245.4

p.V136_N137del1

c.407_409delTCA

1 paper

NM_000245.4

p.S135C

c.403A>T

1 paper

NM_000245.4

p.V136V

c.408C>T

1 paper

NM_000245.4

p.N137H

c.409A>C

1 paper

NM_000245.4

p.N137fs

c.409_410fs

1 paper

NM_000245.4

p.G134S

c.400G>A

1 paper

NM_000245.4

p.N137K

c.411C>A