Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.A152A

c.456T>C

Surrounding Variants

1 paper

NM_000245.4

p.D153_S156delFs

c.457_467del11

1 paper

NM_000245.4

p.A152G

c.455C>G

1 paper

NM_000245.4

p.A152V

c.455C>T

1 paper

NM_000245.4

p.D153Y

c.457G>T

1 paper

NM_000245.4

p.D153A

c.458A>C

1 paper

NM_000245.4

p.D153V

c.458A>T

1 paper

NM_000245.4

p.A152S

c.454G>T

1 paper

NM_000245.4

p.A152fs

c.454_455fs

1 paper

NM_000245.4

p.T151I

c.452C>T

1 paper

NM_000245.4

p.T151delFs

c.453delT

1 paper

NM_000245.4

p.T151S

c.451A>T

1 paper

NM_000245.4

p.I154R

c.461T>G