Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.V158A

c.473T>C

Surrounding Variants

1 paper

NM_000245.4

p.H159Y

c.475C>T

3 papers

NM_000245.4

p.E157G

c.470A>G

1 paper

NM_000245.4

p.H159R

c.476A>G

2 papers

NM_000245.4

p.H159Q

c.477C>A

2 papers

NM_000245.4

p.H159Q

c.477C>G

23 papers

NM_000245.4

p.E157K

c.469G>A

2 papers

NM_000245.4

p.E157*

c.469G>T

3 papers

NM_000245.4

p.S156S

c.468G>A

1 paper

NM_000245.4

p.S156S

c.468G>C

1 paper

NM_000245.4

p.S156S

c.468G>T

1 paper

NM_000245.4

p.C160S

c.478T>A

8 papers

NM_000245.4

p.S156L

c.467C>T