Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.P169delFs

c.507delC

Surrounding Variants

101 papers

NM_000245.4

p.E168D

c.504G>C

105 papers

NM_000245.4

p.E168D

c.504G>T

1 paper

NM_000245.4

p.E168G

c.503A>G

1 paper

NM_000245.4

p.P169S

c.505C>T

1 paper

NM_000245.4

p.P169L

c.506C>T

1 paper

NM_000245.4

p.E167D

c.501A>C

1 paper

NM_000245.4

p.E167D

c.501A>T

1 paper

NM_000245.4

p.P169P

c.507C>A

2 papers

NM_000245.4

p.S170R

c.508A>C

1 paper

NM_000245.4

p.E167G

c.500A>G

3 papers

NM_000245.4

p.E167K

c.499G>A

1 paper

NM_000245.4

p.E167fs

c.499_500fs