Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.C172R

c.514T>C

Surrounding Variants

1 paper

NM_000245.4

p.C172Y

c.515G>A

1 paper

NM_000245.4

p.Q171H

c.513G>C

1 paper

NM_000245.4

p.Q171H

c.513G>T

1 paper

NM_000245.4

p.Q171R

c.512A>G

1 paper

NM_000245.4

p.Q171L

c.512A>T

1 paper

NM_000245.4

p.P173insFs

c.517_518insT

1 paper

NM_000245.4

p.Q171*

c.511C>T

1 paper

NM_000245.4

p.P173S

c.517C>T

2 papers

NM_000245.4

p.S170R

c.510C>A

2 papers

NM_000245.4

p.S170R

c.510C>G

1 paper

NM_000245.4

p.P173R

c.518C>G

1 paper

NM_000245.4

p.P173L

c.518C>T