Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.F192L

c.576C>G

Surrounding Variants

2 papers

NM_000245.4

p.F192L

c.576C>A

1 paper

NM_000245.4

p.F192insFs

c.575_576insA

2 papers

NM_000245.4

p.F192L

c.574T>C

1 paper

NM_000245.4

p.I193insFs

c.578_579insA

1 paper

NM_000245.4

p.R191R

c.573G>A

2 papers

NM_000245.4

p.R191Q

c.572G>A

1 paper

NM_000245.4

p.R191P

c.572G>C

6 papers

NM_000245.4

p.R191W

c.571C>T

1 paper

NM_000245.4

p.F195delFs

c.584delT

1 paper

NM_000245.4

p.F195L

c.583T>C

1 paper

NM_000245.4

p.F195fs

c.583_584fs

1 paper

NM_000245.4

p.F195L

c.585C>A