Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.T200A

c.598A>G

Surrounding Variants

1 paper

NM_000245.4

p.T200S

c.598A>T

1 paper

NM_000245.4

p.T200_I201delFs

c.600_601delCA

1 paper

NM_000245.4

p.T200insFs

c.598dupA

1 paper

NM_000245.4

p.N199S

c.596A>G

1 paper

NM_000245.4

p.N199I

c.596A>T

2 papers

NM_000245.4

p.G198D

c.593G>A

1 paper

NM_000245.4

p.N202D

c.604A>G

1 paper

NM_000245.4

p.G198C

c.592G>T

1 paper

NM_000245.4

p.S204_Y205del1

c.611_613delCTT

1 paper

NM_000245.4

p.V197A

c.590T>C

2 papers

NM_000245.4

p.V197I

c.589G>A

6 papers

NM_000245.4

p.S203T

c.607T>A