Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.H209Y

c.625C>T

Surrounding Variants

2 papers

NM_000245.4

p.H209P

c.626A>C

1 paper

NM_000245.4

p.D208E

c.624T>A

1 paper

NM_000245.4

p.D208D

c.624T>C

1 paper

NM_000245.4

p.D208E

c.624T>G

2 papers

NM_000245.4

p.D208N

c.622G>A

3 papers

NM_000245.4

p.D208Y

c.622G>T

2 papers

NM_000245.4

p.P207R

c.620C>G

4 papers

NM_000245.4

p.F206L

c.618C>G

32 papers

NM_000245.4

p.L211W

c.632T>G

2 papers

NM_000245.4

p.F206Y

c.617T>A

6 papers

NM_000245.4

p.F206S

c.617T>C

1 paper

NM_000245.4

p.H212N

c.634C>A