Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.S233insFs

c.699dupC

Surrounding Variants

1 paper

NM_000245.4

p.Q232Q

c.696G>A

1 paper

NM_000245.4

p.Q232_I235delFs

c.696_705del10

1 paper

NM_000245.4

p.S233S

c.699C>G

1 paper

NM_000245.4

p.Q232insFs

c.694_695insA

1 paper

NM_000245.4

p.Y234fs

c.700_701fs

2 papers

NM_000245.4

p.Y234C

c.701A>G

1 paper

NM_000245.4

p.Y234F

c.701A>T

11 papers

NM_000245.4

p.T230M

c.689C>T

1 paper

NM_000245.4

p.D236_P246del11

c.706_737del33

1 paper

NM_000245.4

p.T230delFs

c.689delC

1 paper

NM_000245.4

p.D236N

c.706G>A

13 papers

NM_000245.4

p.L229F

c.687G>C