Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_000245.4

p.V237delFs

c.710delT

Surrounding Variants

10 papers

NM_000245.4

p.V237fs

c.709_710fs

1 paper

NM_000245.4

p.D236N

c.706G>A

6 papers

NM_000245.4

p.L238fs

c.712_713fs

2 papers

NM_000245.4

p.L238fs

c.712_713fs

1 paper

NM_000245.4

p.L238*

c.713T>A

6 papers

NM_000245.4

p.L238S

c.713T>C

1 paper

NM_000245.4

p.L238*

c.713T>G

1 paper

NM_000245.4

p.D236_P246del11

c.706_737del33

2 papers

NM_000245.4

p.L238F

c.714A>C

1 paper

NM_000245.4

p.L238L

c.714A>G

2 papers

NM_000245.4

p.L238F

c.714A>T

2 papers

NM_000245.4

p.P239H

c.716C>A