Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000245.4

p.F261L

c.783C>A

Surrounding Variants

2 papers

NM_000245.4

p.F261L

c.783C>G

1 paper

NM_000245.4

p.F261F

c.783C>T

2 papers

NM_000245.4

p.F261L

c.781T>C

2 papers

NM_000245.4

p.Y260C

c.779A>G

1 paper

NM_000245.4

p.T263S

c.787A>T

11 papers

NM_000245.4

p.T263M

c.788C>T

1 paper

NM_000245.4

p.Y260H

c.778T>C

1 paper

NM_000245.4

p.T263T

c.789G>T

1 paper

NM_000245.4

p.I259I

c.777T>A

1 paper

NM_000245.4

p.I259V

c.775A>G

1 paper

NM_000245.4

p.V264A

c.791T>C

4 papers

NM_000245.4

p.N257T

c.770A>C