Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.R266M

c.797G>T

Surrounding Variants

1 paper

NM_000245.4

p.R266T

c.797G>C

1 paper

NM_000245.4

p.R266R

c.796A>C

1 paper

NM_000245.4

p.R266G

c.796A>G

2 papers

NM_000245.4

p.R266W

c.796A>T

1 paper

NM_000245.4

p.R266R

c.798G>A

2 papers

NM_000245.4

p.R266S

c.798G>C

2 papers

NM_000245.4

p.R266S

c.798G>T

2 papers

NM_000245.4

p.E267K

c.799G>A

1 paper

NM_000245.4

p.E267A

c.800A>C

1 paper

NM_000245.4

p.T268I

c.803C>T

1 paper

NM_000245.4

p.V264A

c.791T>C

1 paper

NM_000245.4

p.L269I

c.805C>A