Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.M294I

c.882G>T

Surrounding Variants

1 paper

NM_000245.4

p.M294I

c.882G>A

1 paper

NM_000245.4

p.M294I

c.882G>C

1 paper

NM_000245.4

p.P295T

c.883C>A

1 paper

NM_000245.4

p.P295H

c.884C>A

1 paper

NM_000245.4

p.E293_M294insFs

c.879_880insT

2 papers

NM_000245.4

p.L296M

c.886C>A

1 paper

NM_000245.4

p.E293Q

c.877G>C

5 papers

NM_000245.4

p.L296P

c.887T>C

1 paper

NM_000245.4

p.M292I

c.876G>A

1 paper

NM_000245.4

p.M292I

c.876G>C

1 paper

NM_000245.4

p.M292I

c.876G>T

2 papers

NM_000245.4

p.E297G

c.890A>G