Varaico: Literature-Extracted Genetic Variants

MET

3,492 papers

RefSeq Summary

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and be...

Pfam Domains

Semaaa 317–493UCSCSema domain

PSIaa 519–562UCSCPlexin repeat

TIGaa 563–654UCSCIPT/TIG domain

TIGaa 657–739UCSCIPT/TIG domain

TIGaa 742–830UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1078–1337UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

MET proto-oncogene, receptor tyrosine kinase

HGNC Alias Symbols

HGFR; RCCP2; DFNB97

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000245.4

p.E302delFs

c.904_905delGA

Surrounding Variants

10 papers

NM_000245.4

p.T301A

c.901A>G

1 paper

NM_000245.4

p.L300L

c.900C>G

2 papers

NM_000245.4

p.E302K

c.904G>A

1 paper

NM_000245.4

p.E302V

c.905A>T

1 paper

NM_000245.4

p.K303insFs

c.907_908ins13

1 paper

NM_000245.4

p.K303R

c.908A>G

1 paper

NM_000245.4

p.I299V

c.895A>G

1 paper

NM_000245.4

p.I299F

c.895A>T

5 papers

NM_000245.4

p.K303N

c.909G>C

5 papers

NM_000245.4

p.K303N

c.909G>T

1 paper

NM_000245.4

p.R304*

c.910A>T

1 paper

NM_000245.4

p.R304S

c.912A>T